HIGHLIGHTS
- who: G protein-coupled receptor et al. from the University of Campania Luigi Vanvitelli, Italy have published the paper: Pharmacological Insights Into Safety and Ef fi cacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure, in the Journal: (JOURNAL)
- what: The studies show that VCP746 and neladenoson lack renal vasoconstrictor effects in the methoxamine/forskolintreated kidney. The authors comprehensively compared in_vitro, ex vivo, and in_vivo properties of the Frontiers in Pharmacology | www.frontiersin.org investigational A1 R agonist, neladenoson, compared to VCP746, a tool A1R biased agonist.
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