Pharmacological sequestration of mitochondrial calcium uptake protects against dementia and β-amyloid neurotoxicity

HIGHLIGHTS

• who: Elena F. Shevtsova from the InstitutState University have published the research: Pharmacological sequestration of mitochondrial calcium uptake protects against dementia and u03b2-amyloid neurotoxicity, in the Journal: Neurology, London WC1N 3BG, UK. 3Cell Physiology of 29/Nov/2019
• what: The authors have explored the potential neuroprotective effect of Tg-2113x on cellular models of neurodegeneration with calcium overload and u03b2-amyloid toxicity, and in in_vivo models of cognitive dysfunction. This study was performed in line with the principles of the Declaration of Helsinki and was carried out in compliance with the ARRIVE guidelines.
 



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