Pharmacophore-model-based drug repurposing for the identification of the potential inhibitors targeting the allosteric site in dengue virus ns5 rna-dependent rna polymerase

HIGHLIGHTS

• who: Sanjay Kumar et al. from the School of Biotechnology, Jawaharlal Nehru University, New Delhi, India have published the paper: Pharmacophore-Model-Based Drug Repurposing for the Identification of the Potential Inhibitors Targeting the Allosteric Site in Dengue Virus NS5 RNA-Dependent RNA Polymerase, in the Journal: Viruses 2022, 1827 of /2022/
• what: This study reports the in silico testing and validation of FDA-approved drugs against the allosteric_site (N-pocket) of the DENVRdRp domain. This study shows the binding stability of these four approved drug compounds and their binding with DENVRdRp at its allosteric_site . . .
  

   

  

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