Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response

HIGHLIGHTS

  • who: Shawn H. R. Lee from the (UNIVERSITY) have published the Article: Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response, in the Journal: (JOURNAL) of 28/Oct/2022
  • what: The authors evaluated the coefficients of linear regression (u03b2) for each drug, where each unit change in coefficient represents a unit change of MRD (log10-transformed),that is, a coefficient of 0.30 (or log10(2)) indicates that the MRD is twice as high in resistant patients compared to sensitive patients; a coefficient of -0.30 (or log10(0 . . .

     

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