Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/sqstm1 mutants show reduced inner fluidity

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  • who: Mohammad Omar Faruk from the Mohammad Omar Faruk1, Yoshinobu Ichimura1, *, Shun Kageyama1, Satoko Komatsu-Hirota1, Afnan HEl-Gowily1, Yu-shin Sou4, Masato Koike4, Nobuo N. Noda5, and Masaaki Komatsu1, * From the Department of Physiology, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan have published the paper: Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity, in the Journal: (JOURNAL) of October/29,/2021
  • what: The authors propose that the primary defect in ALS/FTD with p62 missense mutations does not involve selective autophagy or the . . .

     

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