Phase separation and ageing of glycine-rich protein from tick adhesive

HIGHLIGHTS

  • What: The authors show that GRP undergoes liquid-liquid phase separation via simple coacervation to form biomolecular condensates in salty environments. The authors provide evidence for protein-rich condensates in natural tick saliva. The authors show that the regularly spaced arginine and aromatic (phenylalanine and tyrosine) residues, separated by glycine-rich regions, are key to the LLPS process via cation-π and π-π interactions.
  • Who: Ketan A. Ganar from the (UNIVERSITY) have published the article: Phase separation and ageing of glycine-rich protein from tick adhesive, in the Journal: (JOURNAL) of 31/03/2023

SUMMARY . . .

 

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