Phase-separation antagonists potently inhibit transcription and broadly increase nucleosome density

HIGHLIGHTS

• who: Rajyalakshmi Meduri from the Rajyalakshmi Meduri, Linda SRubio, Suman Mohajan, and David S. Gross* From the Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA Edited by Brian Strahl have published the paper: Phase-separation antagonists potently inhibit transcription and broadly increase nucleosome density, in the Journal: (JOURNAL) of July/25,/2022
• what: The authors explore the impact of the aliphatic dialcohol, 1,6hexanediol (1,6-HD), on Pol II transcription and nucleosome occupancy in budding yeast. For this analysis, the authors used an H2A-mCherry-expressing diploid . . .
  

   

  

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