Phenome-wide genetic-correlation analysis and genetically informed causal inference of amyotrophic lateral sclerosis

HIGHLIGHTS

• who: Salvatore Du2019Antona from the Institute of Bioimaging and Molecular Physiology, National Research Council, Milan, Italy have published the research: Phenome-wide genetic-correlation analysis and genetically informed causal inference of amyotrophic lateral sclerosis, in the Journal: (JOURNAL)
• what: In the present study, leveraging the genome-wide association statistics from the largest ALS study (van Rheenen et_al 2021), the authors conducted a phenome-wide rg analysis with respect to 957 traits with strong SNP-based heritability estimates (z score > 4) available from the UK Biobank (UKB) (Bycroft et_al 2018). In the present study, the MR . . .
  

   

  

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