Phenotypic plasticity and genetic control in colorectal cancer evolution

HIGHLIGHTS

  • who: Jacob Househam from the (UNIVERSITY) have published the Article: Phenotypic plasticity and genetic control in colorectal cancer evolution, in the Journal: (JOURNAL) of 26/Oct/2022
  • what: The authors show that intratumour genetic ancestry only infrequently affects gene_expression traits and subclonal evolution in colorectal cancer (CRC). In colorectal cancer (CRC), the focus of this study, consensus molecular subtypes (CMS)16 or cancer cell-intrinsic gene_expression subtypes (CRIS)17 exemplify this approach.
  • how: A visual schematic illustrating the main results is shown in Extended Data Fig 9.

SUMMARY

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