Phenotypic screen with the human secretome identifies fgf16 as inducing proliferation of ipsc-derived cardiac progenitor cells

HIGHLIGHTS

  • who: Karin Jennbacken and colleagues from the Department of Protein Science, School of engineering in Chemistry, Biotechnology and Health have published the article: Phenotypic Screen with the Human Secretome Identifies FGF16 as Inducing Proliferation of iPSC-Derived Cardiac Progenitor Cells, in the Journal: (JOURNAL)
  • what: The authors show that FGF16 specifically induced proliferation of CPCs and induced cell-cycle activity in human cardiomyocytes. The authors focused on screening a human secretome library in a proliferation assay with hCPCs. The study was approved by the local Animal Ethics Committee in Gothenburg, Sweden and conducted in adherence . . .

     

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