Phenotypic variation and genetic polymorphism of low-density lipoprotein exon 4 receptor gene among jordanian familial hypercholesterolemia patients

HIGHLIGHTS

  • who: Corresponence to Manar Atoum et al. from the Faculty of Allied Health Sciences, The Hashemite UniversityPO have published the article: Phenotypic variation and genetic polymorphism of low-density lipoprotein exon 4 receptor gene among Jordanian familial hypercholesterolemia patients, in the Journal: (JOURNAL)
  • what: The aim of this study was measure lipid profiles among severe and mild familial hypercholestrolemic (FH) patients and screen unrelated families for LDL receptor (LDLR) gene polymorphism.

SUMMARY

    Many FH exon 4 mutations were reported in the literature: FH Mexico (missense), FH French Canadians (missense), FHPiscataway (deletion . . .

     

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