Pheophytin a inhibits inflammation via suppression of lps-induced nitric oxide synthase-2, prostaglandin e2, and interleukin-1β of macrophages

HIGHLIGHTS

  • who: Chun-Yu Lin and colleagues from the Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan have published the article: Pheophytin a Inhibits Inflammation via Suppression of LPS-Induced Nitric Oxide Synthase-2, Prostaglandin E2, and Interleukin-1β of Macrophages, in the Journal: (JOURNAL)
  • what: The authors demonstrate that pheophytin a can suppress NO production in LPS-stimulated RAW 264.7 cells, possibly due to dual mechanisms of inhibiting NOS2 promoter activities (and hence reducing NOS2 gene_expression and NOS2 protein production) and . . .

     

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