Pho dynamically interacts with spt5 to facilitate transcriptional switches at the hsp70 locus

HIGHLIGHTS

  • who: Allwyn Pereira from the Abbreviations PRC1: Polycomb repressive complex , have published the research: Pho dynamically interacts with Spt5 to facilitate transcriptional switches at the hsp70 locus, in the Journal: (JOURNAL)
  • what: The authors propose that a dynamic interaction switch between PcG proteins and an elongation factor enables stress-inducible genes to efficiently switch between ON/OFF states in the presence/absence of the activating stimulus. Antagonistic binding patterns of HSF and PRC1 at the hsp70 locus To characterise the transcriptional and chromatin dynamics of the heat shock response, the authors focused on the binding . . .

     

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