Phosphatidic acid mediates the nem1-spo7/pah1 phosphatase cascade in yeast lipid synthesis

HIGHLIGHTS

  • who: Joanna M. Kwiatek from the Rutgers Center forRutgers University, New Brunswick, New Jersey, USA have published the paper: Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis, in the Journal: (JOURNAL)
  • what: The aim of this work is to develop a proteoliposome model system that mimics the Nem1-Spo7/Pah1 phosphatase cascade that occurs at the nuclear/ER membrane. The authors developed a model system to examine Pah1 phosphorylation by Pho85-Pho80, the protein kinase that has the greatest effect on Pah1 function , and its dephosphorylation by the membrane-associated . . .

     

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