Phosphatidylinositol 3-kinase class ii α-isoform pi3k-c2α is required for transforming growth factor β-induced smad signaling in endothelial cells*

HIGHLIGHTS

• who: Sho Aki from the lial cells (HMVECs), and mouse lung vascular endothelial cells (MLECs) were plated onto type I collagen (Nitta Gelatin, Osaka, Japan have published the paper: Phosphatidylinositol 3-Kinase Class II α-Isoform PI3K-C2α Is Required for Transforming Growth Factor β-induced Smad Signaling in Endothelial Cells*, in the Journal: (JOURNAL) of July/31,/2014
• what: The authors identified class II PI3K-C2␣ as PI3K isoform that is engaged in TGF␤-induced activation of Smad2/3 signaling.
• how: The data showed that PI3K-C2␣ regulates vesicular trafficking in EC and thereby . . .
  

   

  

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