Phospholipid scramblase 4 (plscr4) regulates adipocyte differentiation via pip3-mediated akt activation

HIGHLIGHTS

  • who: Lisa A. G. Barth and colleagues from the University Hospital for Children and Adolescents, Center for Pediatric Research, Leipzig University, Leipzig, Germany have published the research: Phospholipid Scramblase 4 (PLSCR4) Regulates Adipocyte Differentiation via PIP3-Mediated AKT Activation, in the Journal: (JOURNAL)
  • what: Given the known effect of PLSCR3 knockout on adipose-tissue expansion and the fact that PLSCR4 is significantly downregulated in PTEN-knockdown adipose progenitor cells, the authors propose that PLSCR4 may play a role in lipid accumulation and adipocyte development. Since Plscr3 knockout mice showed a higher accumulation of abdominal fat . . .

     

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