HIGHLIGHTS
- who: Julio Pascual and Marta Crespo from the Capital Medical University, China have published the research work: Phosphorylation of S6RP in peritubular capillaries of kidney grafts and circulating HLA donor-specific antibodies, in the Journal: (JOURNAL)
- how: Showed that treatment with mTORi did not significantly modify C4d staining or phosphorylation of S6RP ERK or mTOR .
SUMMARY
The authors evaluated the activation signals of the mTOR pathway: p-mTOR, p-S6RP and p-ERK, as well as microvascular endothelial proliferation in kidney allografts with histological criteria of ABMR with and without HLA . . .
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