Photocaged histone deacetylase inhibitors as prodrugs in targeted cancer therapy

HIGHLIGHTS

• who: Fabian B. Kraft and collaborators from the Department of Pharmaceutical and Cell Biological Chemistry, Pharmaceutical Institute, University of Bonn, An der Immenburg, Bonn, Germany have published the article: Photocaged Histone Deacetylase Inhibitors as Prodrugs in Targeted Cancer Therapy, in the Journal: Pharmaceuticals 2023, 356 of /2023/
• what: The authors deIn addition, II demonstrated chemosensitizing properties and was capable of reversing scribe the synthesisinand biological evaluation of photocaged prodrugs for both cisplatin resistance cisplatin-resistant Cal27CisR cells . The authors focused the biological evaluation on the prodrug pc-I. The authors have designed and synthesized light . . .
  

   

  

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