Photochemical synthesis of pyrazolines from tetrazoles in flow

HIGHLIGHTS

  • who: Thomas.Loop from the School of, University College, Science Centre have published the research: Photochemical Synthesis of Pyrazolines from Tetrazoles in Flow, in the Journal: (JOURNAL)
  • what: The authors report an alternative approach using UV-light to convert tetrazoles into pyrazolines via a reagent-free strategy. The authors report a continuous photochemical click reaction converting arylated tetrazoles into various pyrazolines and pyrazoles.

SUMMARY

    The union of in situ generated arenediazonium salts 2 and benzamidine hydrochloride thereby rendered the expected adducts 3a-c in high yields which smoothly underwent oxidative cyclization . . .

     

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