Phylogenomic analysis of the diversity of graspetides and proteins involved in their biosynthesis

HIGHLIGHTS

  • who: Kira S. Makarova from the National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA have published the research: Phylogenomic analysis of the diversity of graspetides and proteins involved in their biosynthesis, in the Journal: (JOURNAL)
  • what: The authors attempt a comprehensive analysis of the graspetide-encoding BGCs and report a variety of novel graspetide groups as well as ancillary proteins implicated in graspetide biosynthesis and expression. The authors demonstrate previously unsuspected diversity of graspetide sequences even those associated with closely related ATP-grasp enzymes. The present analysis . . .

     

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