HIGHLIGHTS
- who: Lisanne de Koning and collaborators from the This was a multicenter, observational, cross-sectional studyParticipants were recruited from the Expert Center for MFS and related hereditary connective tissue disorders in Amsterdam, the Netherlands, and the Center for Medical Genetics of the Ghent University Hospital in Belgium. Eligible for inclusion were all children with HCTD, aged between , and , years, who were diagnosed with MFS (9), LDS (12) and genetically confirmed types of EDS, hereafter referred to as EDS (11). The exclusion criteria were comorbid prominent chronic diseases affecting physical functioning, PA, PF, and cognitive impairment (IQ andlt . . .
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