Physiological corticosterone attenuates gp120-mediated microglial activation and is associated with reduced anxiety-like behavior in gp120-expressing mice

HIGHLIGHTS

  • who: Emaya M. Moss and collaborators from the Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, University, MS, USA have published the research: Physiological Corticosterone Attenuates gp120-Mediated Microglial Activation and Is Associated with Reduced Anxiety-Like Behavior in gp120-Expressing Mice, in the Journal: Viruses 2023, 15, 424. of /2023/
  • what: The authors aimed to assess the ameliorative capacity of glucocorticoids on gp120-mediated neuroinflammation and the affective consequences of gp120 on HPA dysregulation in a whole animal model.
  • how: The authors conducted parallel in vitro and in vivo studies . . .

     

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