Physiological levels of estradiol limit murine osteoarthritis progression

HIGHLIGHTS

  • who: Endocrinology and collaborators from the University of Gothenburg, Gothenburg, Sweden Turku, Finland have published the research work: Physiological levels of estradiol limit murine osteoarthritis progression, in the Journal: (JOURNAL)
  • what: The aim of this study was to determine whether deficiency of female sex steroids affects OA progression and to evaluate the protective effect of treatment with a physiological dose of 17u03b2-estradiol (E2) on OA progression using a murine model. This study shows that treatment with a physiological dose of E2 exerts a protective role by reducing OA symptoms. The experiments were carried out . . .

     

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