Physiologically based modelling of the antiplatelet effect of aspirin: a tool to characterize drug responsiveness and inform precision dosing

HIGHLIGHTS

  • who: Alberto Giaretta and colleagues from the Department of Information Engineering, University of Padova, Padova, Italy, Department of Pathology have published the article: Physiologically based modelling of the antiplatelet effect of aspirin: A tool to characterize drug responsiveness and inform precision dosing, in the Journal: PLOS ONE of 25/Oct/2021
  • what: The authors applied a previously described PB model of the antiplatelet effect of low-dose aspirin to characterize the determinants of the extent and duration of platelet cyclooxygenase (COX)-1 inhibition to help designing precision dosing regimens in patients with accelerated platelet turnover . . .

     

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