Pi(18:1/18:1) is a scd1-derived lipokine that limits stress signaling

HIGHLIGHTS

• who: Maria Thu00fcrmer from the University Jena, Jena, Germany have published the research work: PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors report on the identification of 1,2-dioleoyl-sn-glycero-3-phospho-(1`-myo-inositol) as SCD1derived lipokine that promotes cell survival and counteracts 2 cellular stress responses by interfering with stress-activated pathways, i.e., p38 MAPK signaling, the UPR, and autophagy. Together, the authors show that programmed cell death (i) inhibits SCD1 expression, (ii) reduces . . .
  

   

  

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