Pi(4,5)p diffuses freely in the plasma membrane even within high-density effector protein complexes

HIGHLIGHTS

• who: Jonathan Pacheco and colleagues from the Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA have published the paper: PI(4,5)P diffuses freely in the plasma membrane even within high-density effector protein complexes, in the Journal: (JOURNAL) of 05/03/2023
• what: The authors determine diffusion at PI(4,5)P2-dependent macromolecular complexes, labeled by expression of fluorescently tagged transgenes or incorporation of such tags onto endogenous proteins by gene editing. The authors report that, for the most part, free PI(4,5)P2 diffuses unhindered inside . . .
  

   

  

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