Pickpocket1 is an ionotropic molecular sensory transducer*

HIGHLIGHTS

• who: Nina Boiko from the Nina Boiko, Volodymyr Kucher, James DStockand1, and Benjamin A. Eaton1, From the Department of Physiology, University of Texas Health Sciences Center, San Antonio, Texas , Background: Ion channels are candidate molecules for transforming external stimuli into neural activity during sensory perception. Results: Pickpocket, encodes an acid-sensing ion channel (ASIC) that is sufficient to drive neural activity in sensory neurons. Conclusions: The perception of external acid by Pickpocket, channels is sufficient to produce phasic sensory neuron activity. Significance: ASIC channels can function as molecular sensory transducers in sensory neurons. The molecular transformation of . . .
  

   

  

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