Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice

HIGHLIGHTS

• who: Ze-Yan Yu from the Cardiac Research Institute University of have published the article: Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice, in the Journal: (JOURNAL) of 11/09/2021
• what: The authors show that Piezo1 only colocalizes with TRPM4 in cardiomyocytes that these channels physically interact providing a basis for their functional coupling. The results from this analysis showed that there were no significant differences in body weight (Extended Data Fig 2e) heart rate (Extended Data Fig 2f) cardiac function (Extended Data Fig 2g . . .
  

   

  

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