HIGHLIGHTS
- who: CDCP and colleagues from the Department, Cleveland Clinic, Cleveland, Ohio, USAUniversity of have published the paper: pigmented epithelial barrier integrity for the development of experimental autoimmune uveitis, in the Journal: Rheumatology and Clinical Autoimmunity Center of Excellence,
SUMMARY
Experimental autoimmune uveitis (EAU) is the best available in_vivo model for autoimmune posterior uveitis. In EAU, and likely in autoimmune uveitis, research evidence has established that pathogenic T_cells autoreactive to retinal antigen(s) are primed in the periphery and migrate through the blood-retina barrier (BRB), which is composed of the retinal pigment epithelium . . .
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