Pinocembrin suppresses oxidized low-density lipoprotein-triggered nlrp3 inflammasome/gsdmd-mediated endothelial cell pyroptosis through an nrf2-dependent signaling pathway

HIGHLIGHTS

• who: Tong Wang from the CollegeShandong University have published the research: Pinocembrin suppresses oxidized low-density lipoprotein-triggered NLRP3 inflammasome/GSDMD-mediated endothelial cell pyroptosis through an Nrf2-dependent signaling pathway, in the Journal: Scientific Reports Scientific Reports
• what: The authors show that oxLDL stimulated cytotoxicity in HUVECs. AS is known to be an inflammatory disease involving endothelial dysfunction, therefore, the study provides novel insights into the development of Pin as a therapeutic strategy for AS.
• how: Data are described with mean ± SD of at least 3 different experiments. *P and amplt 0 . . .
  

   

  

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