Pioglitazone hydrochloride extends the lifespan of caenorhabditis elegans by activating daf-16/foxo- and skn- 1/nrf2-related signaling pathways

HIGHLIGHTS

  • who: Wenjuan Jia and collaborators from the Department of Endocrinology and Metabolism, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China have published the article: Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF-16/FOXO- and SKN- 1/NRF2-Related Signaling Pathways, in the Journal: Oxidative Medicine and Cellular Longevity of 29/05/2022
  • what: The authors used Caenorhabditis elegans (C. elegans) as a model to investigate the mechanism of delaying aging induced by PGZ.
  • how: The results showed that diverse concentrations of PGZ were capable of increasing the lifespan . . .

     

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