Pioneer of prostate cancer: past, present and the future of foxa1

HIGHLIGHTS

  • who: Mona Teng from the Princess Margaret Cancer Centre, University Health Network, Toronto, Canada have published the article: Pioneer of prostate cancer: past, present and the future of FOXA1, in the Journal: (JOURNAL)
  • what: Recent functional characterization of FOXA1 mutants shed light on their complex modes of action in driving prostate cancer where the function may be divergent depending on the residues affected.
  • future: Considering the prevalence and differential FOXA1 activity conferred by specific FOXA1 mutations future studies may consider conducting inhibition-screens with FOXA1 mutant model systems. Based on the varying function . . .

     

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