Pitx2 differentially regulates the distinct phases of myogenic program and delineates satellite cell lineages during muscle development

HIGHLIGHTS

• who: Felícitas Ramírez de Acuña et al. from the Cardiac and Skeletal Myogenesis Group, Department of Experimental, University of Jaen, Jaén, Spain, Cardiac and have published the research: Pitx2 Differentially Regulates the Distinct Phases of Myogenic Program and Delineates Satellite Cell Lineages During Muscle Development, in the Journal: (JOURNAL)
• what: The authors show that in_vivo inactivation of Pitx2 in early predetermined uncommitted MPCs by using the Pax3Cre/Wt deleter line leads to defective cell proliferation and migration of MPCs generating muscle hypotrophy.
• how: These results showed that inactivation of . . .
  

   

  

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