Pkc-ζ mediated reduction of the extracellular vesicles-associated tgf-β1 overcomes radiotherapy resistance in breast cancer

HIGHLIGHTS

• who: Fayun Zhang from the the ethics committees at Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China have published the article: PKC-u03b6 mediated reduction of the extracellular vesicles-associated TGF-u03b21 overcomes radiotherapy resistance in breast cancer, in the Journal: (JOURNAL)
• what: As PKCs have been reported to be involved in the secretion of EVs, to understand the underlying mechanism of the TGF-u03b21EV secretion, the authors focused on PKCs. The authors demonstrated that irradiation induced a significant increase of PKC-u03b6 expressions on three levels, including the level of . . .
  

   

  

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