Pkceta promotes stress-induced autophagy and senescence in breast cancer cells, presenting a target for therapy

HIGHLIGHTS

• who: Noa Rotem-Dai and colleagues from the Ben-Gurion University of the Negev, Beer Sheva, Israel have published the Article: PKCeta Promotes Stress-Induced Autophagy and Senescence in Breast Cancer Cells, Presenting a Target for Therapy, in the Journal: Pharmaceutics 2022, 14, 1704. of /2022/
• what: The authors show that PKCη promotes autophagy induced by ER and oxidative stress and facilitates the transition from autophagy to senescence. The authors demonstrate that PKCη knockdown reduces both the autophagic flux and markers of senescence. The study proposes PKCη as a target for therapeutic intervention acting in . . .
  

   

  

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