Pkn2 deficiency leads both to prenatal ‘ congenital cardiomyopathy and defective angiotensin ii stress responses

HIGHLIGHTS

• who: George` and collaborators from the Protein Phosphorylation Laboratory, Francis Crick Institute, Midland Road, AT, UKProtein Phosphorylation Laboratory, Francis Crick Institute, Midland Road, AT have published the article: PKN2 deficiency leads both to prenatal u2018 congenital cardiomyopathy and defective angiotensin II stress responses, in the Journal: (JOURNAL) of 30/05/2022
• what: The authors demonstrate that the loss of PKN2 in cardiomyocytes has a catastrophic effect on ventricular myocardial development, suggesting that alterations in PKN2 signalling may contribute to congenital cardiac problems/cardiomyopathy. To assess whether altered expression might impact this response and in view . . .
  

   

  

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