Pkr and tlr3 trigger distinct signals that coordinate the induction of antiviral apoptosis

HIGHLIGHTS

  • who: Wenjie Zuo from the (UNIVERSITY) have published the research work: PKR and TLR3 trigger distinct signals that coordinate the induction of antiviral apoptosis, in the Journal: (JOURNAL) of 13/07/2022
  • what: This study investigated the mechanisms underlying dsRNA-induced cell death, particularly the involvement of RLRs, TLR3, and PKR. The authors focused on cFLIP and analyzed the effects of the inhibition of translation by CHX and the activation of PKR on cFLIP levels.
  • how: These results indicated that the delivery of RNA/protein into the cell cytoplasm by microinjections triggered rapid . . .

     

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