Pkr-mediated phosphorylation of eif2a and chk1 is associated with doxorubicin-mediated apoptosis in hcc1143 triple-negative breast cancer cells

HIGHLIGHTS

  • who: Sol Lee and colleagues from the Department of Biological Sciences, Konkuk University, Neungdong-ro, Gwangin-gu, Seoul, Republic of Korea have published the research work: PKR-Mediated Phosphorylation of eIF2a and CHK1 Is Associated with Doxorubicin-Mediated Apoptosis in HCC1143 Triple-Negative Breast Cancer Cells, in the Journal: (JOURNAL)
  • what: The authors investigated the roles of and its downstream players in doxorubicin-treated cancer cells.
  • how: CHK1 Phosphorylation in HCC1143 Cells Since the data showed that PKR inhibition reduced doxorubicin-mediated apoptosis in HCC1143 cells the authors investigated the signaling pathways involved . . .

     

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