Pla2g7/paf-ah as potential negative regulator of the wnt signaling pathway mediates protective effects in brca1 mutant breast cancer

HIGHLIGHTS

  • who: Yue Liao and colleagues from the Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany have published the Article: PLA2G7/PAF-AH as Potential Negative Regulator of the Wnt Signaling Pathway Mediates Protective Effects in BRCA1 Mutant Breast Cancer, in the Journal: (JOURNAL)
  • what: The authors analyze the functional impact of on BRCA1 and explore its relationship to the By performing immunohistochemistry expression and expression were examined in both BRCA1 WT and BRCA1 specimens. By functional assays in HCC1937 cells, the authors show that the loss of PAF-AH leads to cancer . . .

     

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