Placental expression of estrogen-related receptor gamma is reduced in fetal growth restriction pregnancies and is mediated by hypoxia

HIGHLIGHTS

  • who: Advance access publication date and colleagues from the University of Manchester, Manchester, UK have published the research: Placental expression of estrogen-related receptor gamma is reduced in fetal growth restriction pregnancies and is mediated by hypoxia, in the Journal: (JOURNAL)
  • what: This study shows that both mRNA and protein expression of ESRRG and the mRNA expression of its downstream genes are decreased in placentas from pregnancies complicated by Placental hypoxia and ESRRG signals, 2022, Vol. This model has previously been well characterized and reproduces aspects of FGR, including reduced trophoblast proliferation and increased apoptosis . . .

     

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