Placental galectins regulate innate and adaptive immune responses in pregnancy

HIGHLIGHTS

  • who: Orsolya Oravecz and collaborators from the The University of Newcastle, Australia have published the Article: Placental galectins regulate innate and adaptive immune responses in pregnancy, in the Journal: (JOURNAL)
  • what: The authors show that gal-13 and gal-14 bind to the surface of nonactivated PBMCs (monocytes, natural killer cells, B cells, and T_cells) and increase their viability while decreasing the rate of their apoptosis without promoting cell proliferation. To further characterize the role of placenta-specific galectins in the regulation of maternal-fetal immune interactions, the authors aimed to investigate the effects of . . .

     

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