Placental sex-dependent spermine synthesis regulates trophoblast gene expression through acetyl-coa metabolism and histone acetylation

HIGHLIGHTS

• who: Irving L. M. H. Aye from the University of have published the article: Placental sex-dependent spermine synthesis regulates trophoblast gene expression through acetyl-coA metabolism and histone acetylation, in the Journal: (JOURNAL) of 24/05/2022
• what: The authors focused on H3K27Ac because it is a robust mark of active promoters and distal enhancers that are tightly coupled to gene expression and transcription factor binding22 23 and previous studies had shown that alterations in this histone mark was associated with foetal growth restriction24. The authors focused on HSD3B1 as this enzyme plays a . . .
  

   

  

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