Placental stem cells-derived exosomes stimulate cutaneous wound regeneration via engrailed-1 inhibition

HIGHLIGHTS

  • who: . et al. from the Onlus, Italy Manchester Metropolitan University have published the Article: Placental stem cells-derived exosomes stimulate cutaneous wound regeneration via engrailed-1 inhibition, in the Journal: (JOURNAL)
  • what: This study investigated the effects and mechanism of pMSCs and pMSC-exos on wound regeneration using a fullthickness rat model. The study showed that MMP1 and MMP3 were significantly up-regulated, whereas TIMP1 and TIMP3 were down-regulated treated by pMSCexos. The authors prepared the exosomes from the pMSCs; and evaluated their effects on wound regeneration via a full-thickness Frontiers in Bioengineering . . .

     

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