Plantaricin bm-1 decreases viability of sw480 human colorectal cancer cells by inducing caspase-dependent apoptosis

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  • who: ufeffHeufeff ufeffWangufeff et al. from the Federal University of Parau00edba, Brazil have published the research: Plantaricin BM-1 decreases viability of SW480 human colorectal cancer cells by inducing caspase-dependent apoptosis, in the Journal: (JOURNAL)
  • what: The authors investigated whether plantaricin BM-1 has anticancer activity against SW480 CRC cells. This study provides an experimental basis for further development of plantaricin BM-1 as an anti-colorectal cancer compound. Deoxypodophyllotoxin has also been confirmed to mediate the intrinsic mitochondrial pathway to induce CRC cell apoptosis by increasing the level of pro-apoptotic protein Bax . . .

     

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