Plasma branched-chain and aromatic amino acids correlate with the gut microbiota and severity of parkinson’s disease

HIGHLIGHTS

• who: Yi Zhang from the Participant recruitment and data collection One hundred six individuals with PD were recruited from the Movement Disorders Clinic at the Department of Neurology and Institute of Neurology, Ruijin HospitalPD was diagnosed according to the United Kingdom Parkinson`s Disease Society Brain Bank criteria53. Exclusion criteria for PD patients were: (1) atypical or secondary parkinsonism, (2) serious chronic illnesses (e_g, diabetes, heart failure, liver cirrhosis, malignancy, hematological or autoimmune diseases, or inflammatory gastrointestinal disease), (3) the use of probiotic or antibiotic supplements for the three months before enrollment, or (4) a high- or . . .
  

   

  

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