Plasmacytoid dendritic cells appear inactive during sub-microscopic plasmodium falciparum blood-stage infection, yet retain their ability to respond to tlr stimulation

HIGHLIGHTS

  • who: Jessica R. Loughland from the Menzies School of Health Research, Darwin, Australia and Charles Darwin University, Darwin, Australia Centre for have published the research: Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation, in the Journal: Scientific Reports Scientific Reports of 24/01/2017
  • what: The authors show for the first time that pDC are apoptotic during the higher dose P. falciparum infection. The authors show active caspase-3 detection by flow cytometry in pDC increased in the 1,800 pRBC . . .

     

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