HIGHLIGHTS
- who: Dickson Donu and collaborators from the Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA, USA have published the article: Plasmodium falciparum Nicotinamidase as A Novel Antimalarial Target, in the Journal: Biomolecules 2022, 1109 of /2022/
- what: The authors demonstrated that 5-Me-nicotinaldehyde inhibits Pf Nic activity in parasite lysates.
SUMMARY
Because NAM is formed + turnover formedfrom readily from rapid NAD+ turnover in mammalian the most prevalent prereadily rapid NAD in mammalian cells,cells, the most prevalent precursor to + in the body is NAM. The only salvage enzyme that . . .
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