Platelet-Activating Factor-Receptor Signaling Mediates Targeted Therapies-Induced Microvesicle Particles Release in Lung Cancer Cells

HIGHLIGHTS

  • who: Shreepa J. Chauhan and collaborators from the Department of Pharmacology and Toxicology, Boonshoft School of Medicine Wright State University, Department of Dermatology, Wright State Physicians, Wright State University, Dayton, OH, USA have published the research work: Platelet-Activating Factor-Receptor Signaling Mediates Targeted Therapies-Induced Microvesicle Particles Release in Lung Cancer Cells, in the Journal: (JOURNAL)
  • what: As most therapeutic agents act as pro-oxidative stressors this studies were designed to determine the role of the PAFR signaling in targeted therapies (i.e. gefitinib and erlotinib)-mediated MVP release and underlying mechanisms using PAFR . . .

     

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