Platelet-derived microrna-223 attenuates tnf-α induced monocytes adhesion to arterial endothelium by targeting icam-1 in kawas

HIGHLIGHTS

• who: Manli Guo from the Southern Medical University, China have published the article: Platelet-derived microRNA-223 attenuates TNF-α induced monocytes adhesion to arterial endothelium by targeting ICAM-1 in Kawas, in the Journal: (JOURNAL)
• what: The authors demonstrate that KD platelet-derived miR-223 inhibits the endothelial expression of ICAM-1, at least in part contributing to attenuating the adhesion of inflammatory cells (e_g, monocytes) in KD vasculitis. In the present study, the results showed that KD platelets with a higher level of miR-223 were incorporated into HCAECs, resulting in the horizontal transfer . . .
  

   

  

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