Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm

HIGHLIGHTS

  • who: . et al. from the Monzino Cardiology Center (IRCCS), Italy University Hospital Mu00fcnster, Germany have published the Article: Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm, in the Journal: (JOURNAL)
  • how: The authors analyzed plasma and platelets isolated from patients with AAA and platelet-specific Panx1 deficient mice in the PPE model that mimics human AAA pathology (Busch et_al 2021).
  • future: Experiments are needed to analyze the independent contribution of endothelial cells and platelets in experimental AAA formation and progression.

SUMMARY

     

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